I have a lot going after a major setback about a week ago. This sciatica was hurting to the point that I was crying from the pain just while doing normal things like showers, cooking etc. I tried taking 3x my dose of Tramadol, didn't help or make a bit of differance. So I took it upon myself to take 180 ibuprofen..landed myself back in the Looney bin cause, never fails, I told on myself. Supposedly I should have died from that much .. If I hadn't said anything, I would have had irreversible kidney